||Bioinspired Multiscale Systems for Tissue Regeneration and Cancer Therapy
讲座题目: Bioinspired Multiscale Systems for Tissue Regeneration and Cancer Therapy
讲座时间: 2017年7月18日（星期二） 上午 10：00
讲座人: Xiaoming He 教授
讲座摘要：Over the past decades, tremendous advancements have been made in discovering new therapeutic agents for medicine from the traditional small molecules to peptides/proteins, genetic materials, and more recently cells and tissues. However, the challenge to safely and effectively deliver these agents from their procurement to the clinical use in human body is still enormous. The issues range from poor bioavailability, systemic toxicity, and low specificity for the acellular agents, to poor survival after long-term storage, non-physiological cultivation in vitro, and immune rejection in vivo for cell-based medicine. We have been working on addressing these issues facing today’s medicine using a bioinspired multiscale engineering approach. In this talk, I will show our recent data on developing and utilizing novel bioinspired multiscale biomaterials and devices to engineer various normal and cancer stem cells and immune cells for treating ischemic diseases, modulating immune reactions, and fighting against cancer.
Xiaoming “Shawn” He is a Professor of Biomedical Engineering at The Ohio State University (OSU), Columbus, Ohio. His current research is focused on developing micro and nanoscale biomaterials and devices to engineer totipotent, pluripotent, and multipotent stem cells for tissue regeneration, cancer therapy, and assisted reproduction. His research has been funded with him as the PI by various private foundations and government agencies including American Cancer Society (ACS Research Scholar Grant), NSF (two standard grants), and NIH (four R01 grants). He has published more than 90 peer-reviewed articles in high ranking journals such as Nature Communications, ACS Central Science, Advanced Materials, and ACS Nano, in addition to one book, three book chapters, and more than 55 conference publications.